PORCINE TNF - A REVIEW

One of the classical animal model systems in the study of important ca rdiovascular diseases, such as septic shock is that of swine. Importan t mediators of such disease states are different cytokines, among them tumor necrosis factor alpha (TNF-alpha) and beta (TNF-beta). This rev iew aims to summarize the current knowledge about the primary structur e and the regulation of the porcine TNF genes, as well as methods used to measure their respective proteins.