INDICATIONS, TECHNIQUES AND RESULTS OF POSTOPERATIVE BRACHYTHERAPY INCANCER OF THE ORAL CAVITY

Citation
M. Pernot et al., INDICATIONS, TECHNIQUES AND RESULTS OF POSTOPERATIVE BRACHYTHERAPY INCANCER OF THE ORAL CAVITY, Radiotherapy and oncology, 35(3), 1995, pp. 186-192
Citations number
20
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Journal title
ISSN journal
01678140
Volume
35
Issue
3
Year of publication
1995
Pages
186 - 192
Database
ISI
SICI code
0167-8140(1995)35:3<186:ITAROP>2.0.ZU;2-A
Abstract
Purpose/objective: We tried to reduce the number of local recurrences after surgery and external beam irradiation (EBI) in carcinoma of the oral cavity, when margins were positive or close. Material and methods : From 1980 to 1992, we treated 97 cases of carcinomas of the oral cav ity by postoperative brachytherapy. Surgery was combined with EBI+brac hytherapy in 51 cases and with brachytherapy alone in 46 cases. We tre ated 29 T1, 34 T2, 30 T3T4 and four Tx (73% were NO at first examinati on and 23% had positive nodes). The type of surgery is analysed. Brach ytherapy was performed in one or two planes along the surgical scar. I f the mandibular rim was resected, especially when the tongue or the r emaining floor were sutured to the internal face of the inferior lip o r to the buccal mucosa, the bridge technique was used. To decrease the dose to the inferior part of the mandible, the bridge was modified th anks to experimental dosimetry. Results: At 5 years, the local control (LC) is 89%, the locoregional control (LRC) 82%, the specific surviva l (SS) 74% and the overall survival (OS) 67%. Complications: We noted 19% of grade 1 (minor), 12% of grade 2 (moderate) and 6% of grade 3 (m ajor) complications. Conclusion: Compared with the results of the lite rature, we think that postoperative brachytherapy can improve classica l radiosurgical results in selected cases with a risk of local recurre nce.