M. Pernot et al., INDICATIONS, TECHNIQUES AND RESULTS OF POSTOPERATIVE BRACHYTHERAPY INCANCER OF THE ORAL CAVITY, Radiotherapy and oncology, 35(3), 1995, pp. 186-192
Citations number
20
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Purpose/objective: We tried to reduce the number of local recurrences
after surgery and external beam irradiation (EBI) in carcinoma of the
oral cavity, when margins were positive or close. Material and methods
: From 1980 to 1992, we treated 97 cases of carcinomas of the oral cav
ity by postoperative brachytherapy. Surgery was combined with EBI+brac
hytherapy in 51 cases and with brachytherapy alone in 46 cases. We tre
ated 29 T1, 34 T2, 30 T3T4 and four Tx (73% were NO at first examinati
on and 23% had positive nodes). The type of surgery is analysed. Brach
ytherapy was performed in one or two planes along the surgical scar. I
f the mandibular rim was resected, especially when the tongue or the r
emaining floor were sutured to the internal face of the inferior lip o
r to the buccal mucosa, the bridge technique was used. To decrease the
dose to the inferior part of the mandible, the bridge was modified th
anks to experimental dosimetry. Results: At 5 years, the local control
(LC) is 89%, the locoregional control (LRC) 82%, the specific surviva
l (SS) 74% and the overall survival (OS) 67%. Complications: We noted
19% of grade 1 (minor), 12% of grade 2 (moderate) and 6% of grade 3 (m
ajor) complications. Conclusion: Compared with the results of the lite
rature, we think that postoperative brachytherapy can improve classica
l radiosurgical results in selected cases with a risk of local recurre
nce.