V. Bogdanic et al., DONOR BUFFY-COAT INFUSION AND CHEMOTHERAPY FOR LEUKEMIA IN RELAPSE AFTER MARROW TRANSPLANTATION, Haematologica, 80(4), 1995, pp. 338-340
A patient relapsing with blastic lymphoid transformation of chronic my
eloid leukemia after bone marrow transplantation received donor buffy-
coat infusion. Low-dose chemotherapy was added because of a rapid WBC
increase. Complete hematologic and cytogenetic remission was obtained.
The patient remained in complete hematologic and cytogenetic remissio
n for four months until he died in an accident. Two patients with acut
e leukemia failed to respond to a similar treatment.