STEREOSELECTIVE SYNTHESIS OF OLIGO(TETRAHYDROFURANS) - LINEAR AND CONVERGENT ROUTES TO BITETRAHYDROFURANS AND TERTETRAHYDROFURANS

Authors
KOERT U STEIN M WAGNER H
Citation
U. Koert et al., STEREOSELECTIVE SYNTHESIS OF OLIGO(TETRAHYDROFURANS) - LINEAR AND CONVERGENT ROUTES TO BITETRAHYDROFURANS AND TERTETRAHYDROFURANS, Liebigs Annalen, (8), 1995, pp. 1415-1426
Citations number
26
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen → ACNP
ISSN journal
09473440
Issue
8
Year of publication
1995
Pages
1415 - 1426
Database
ISI
SICI code
0947-3440(1995):8<1415:SSOO-L>2.0.ZU;2-X
Abstract
The ''dimeric'' and ''trimeric'' oligo (tetrahydrofurans) (oligo-THFs) 24, 28,32, and 38 were synthesized stereoselectively according to a l inear and a convergent synthetic strategy. The oligo-THFs thus obtaine d are important intermediates for the synthesis of artificial ion chan nels. Furthermore, they can be used in the total synthesis of Annonace ae acetogenins, a class of natural occurring oligo-THFs with promising pharmacological properties.