Ds. Raso et Wb. Greene, SYNOVIAL METAPLASIA OF A PERIPROSTHETIC CAPSULE SURROUNDING A POLYURETHANE FOAM BREAST PROSTHESIS, Annals of plastic surgery, 35(2), 1995, pp. 201-203
A 43-year-old woman underwent two-stage bilateral reconstruction mammo
plasty using silicone-filled, polyurethane foam-covered breast implant
s. The permanent implants were later removed, The periprosthetic capsu
le demonstrated synovial metaplasia by light and electron microscopy,
Synovial metaplasia is believed to be induced by the physical and chem
ical characteristics of the prostheses and may have important clinical
implications in reducing capsular contracture and increasing host acc
eptance of implantable biomaterials.