BOVINE VIRAL DIARRHEA VIRUS-INFECTION IN BONE-MARROW OF EXPERIMENTALLY INFECTED CALVES

Authors
SPAGNUOLO M KENNEDY S FOSTER JC MOFFETT DA ADAIR BM
Citation
M. Spagnuolo et al., BOVINE VIRAL DIARRHEA VIRUS-INFECTION IN BONE-MARROW OF EXPERIMENTALLY INFECTED CALVES, Journal of Comparative Pathology, 116(1), 1997, pp. 97-100
Citations number
15
Categorie Soggetti
Pathology,"Veterinary Sciences
Journal title
Journal of Comparative Pathology → ACNP
ISSN journal
00219975
Volume
116
Issue
1
Year of publication
1997
Pages
97 - 100
Database
ISI
SICI code
0021-9975(1997)116:1<97:BVDVIB>2.0.ZU;2-N
Abstract
Colostrum-deprived calves were inoculated with either a field isolate of bovine viral diarrhoea virus (BVDV) containing cytopathogenic (CP) and noncytopathogenic (NCP) biotypes or with only the NCP biotype. Par affin wax-embedded sections of bone marrow from these calves, examined by means of an immunoperoxidase method, showed BVDV antigen in megaka ryocytes and myeloid cells. Infection of such cells may play a role in the pathogenesis of thrombocytopenia, leucopenia and neutropenia, as reported in cattle infected with BVDV. (C) 1997 W.B. Saunders Company Limited.