AGGRESSIVE PLEOMORPHIC CD2-, CD56+ LYMPHOMA WITH T(5-9)(Q31-Q34) ABNORMALITY(, CD3)

CD56-positive lymphoma is a recently described entity which is charact erized by predominantly extranodal involvement and on aggressive clini cal course. We report one such case with involvement of the bone marro w and spinal cord at presentation, and associated with reactive hemoph agocytic syndrome. The lymphoma cells had a highly pleomorphic appeara nce which is uncommon in CD56-positive lymphoma. Cytogenetic studies r evealed a t(5;9)(q31;q34) abnormality. Analysis of more cases is requi red to determine if this is a recurring chromosomal translocation char acteristic of the group of aggressive CD56-positive lymphoma.