HIGHLY STEREOSELECTIVE ALKYLATION AT NEOPENTYL POSITION ON BETA,BETA-DIALKYL SUBSTITUTED GAMMA-BUTYROLACTONE RING

Authors
UENISHI J TATSUMI Y KOBAYASHI N YONEMITSU O
Citation
J. Uenishi et al., HIGHLY STEREOSELECTIVE ALKYLATION AT NEOPENTYL POSITION ON BETA,BETA-DIALKYL SUBSTITUTED GAMMA-BUTYROLACTONE RING, Tetrahedron letters, 36(33), 1995, pp. 5909-5912
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
33
Year of publication
1995
Pages
5909 - 5912
Database
ISI
SICI code
0040-4039(1995)36:33<5909:HSAANP>2.0.ZU;2-B
Abstract
The alpha-alkylation of t-butyldiphenylsilyl)oxymethyl-gamma-butyrolac tone enolates by alkyl trifluoromethanesulfonate or dimethyl sulfate g ives consecutive quaternary and tertiary, or two quaternary carbon cen ters with high diastereoselectivities.