TACTILE RESOLUTION - PERIPHERAL NEURAL MECHANISMS UNDERLYING THE HUMAN CAPACITY TO DETERMINE POSITIONS OF OBJECTS CONTACTING THE FINGERPAD

We measured the ability of humans to discriminate the positions of sph erical objects passively contacting the fingerpad. The discrimination threshold averaged 0.55 mm for a moderately curved sphere (radius 5.80 mm) and decreased to 0.38 mm for a more curved sphere (radius 1.92 mm ); since the receptor density is about 1 per mm(2), these values are s ubstantially smaller than those predicted by the sampling theorem (ref erred to as hyperacuity). To elucidate the underlying neural mechanism s, responses to the same spheres and random sequences of stimuli were recorded from single Merkel afferents (SAIs) and Meissner afferents (R As) in anesthetized monkeys. For multiple applications of identical st imuli, coefficients of variation of responses were around 3%. Profiles of responses across the SAI population were ''hill-shaped.'' A change in position of the stimulus on the skin resulted in a matching shift of the profile, evident over the whole profile for the more curved sph ere but only at the skirts for the less curved sphere. The shift in re sponse profiles, relative to the standard deviations, increased as the change in position increased, and was more reliable for the more curv ed sphere. Responses were measured over four time frames: 0.2, 0.3, 0. 5, and 1.0 sec. Although responses increased with an increase in integ ration time, so, too, did their standard deviations, so that signal-to -noise ratios or the resolution in the SAI population was about the sa me at 0.2 sec as at 1.0 sec. Only half the RAs responded; responses we re small, but signalled reliable information about the position of the stimulus.