RENAL-TRANSPLANTATION IN PATIENTS WITH POSTERIOR URETHRAL VALVES - FAVORABLE LONG-TERM OUTCOME

Purpose: We assessed the long-term efficacy of renal transplantation i n patients with posterior urethral valves. Materials and Methods: We r eviewed the outcome in 23 patients with posterior urethral valves who underwent renal transplantation since 1979. Results: Graft survival wa s 69% at 5 years and 63% at 10 years. Seven patients with followup of 7 years or longer had a mean serum creatinine level of 1.5 mg./dl. Thr ee patients (13%) demonstrated significant bladder dysfunction postope ratively. Conclusions: Renal transplantation into a valve bladder is n ot associated with an abnormally high rate of failure. Deterioration o f graft function secondary to lower urinary tract dysfunction is uncom mon, with the majority of patients able to use the unmodified native b ladder as a receptacle for the transplanted kidney.