CHANGES OF NEUROENDOCRINE AXES IN PATIENTS WITH MENSTRUAL MIGRAINE

Menstrual migraine (MM) is a menstrually related disorder (MRD) charac terized by several symptoms in common with premenstrual syndrome (PMS) . It has been hypothesized that in both MM and PMS hormonal cyclicity could change the balance of neurotransmitters and neuromodulators like monoamine and opioid. In this article we analyze all the data collect ed by our group on the central opioid tonus and the adrenergic and ser otonergic systems in patients affected by menstrual migraine.