Blastomyces is a pathogen that may infect healthy and immunocompromise
d hosts, Frequently entering the lungs, the initial pneumonitis usuall
y is followed by skin and bony involvement secondary to hematogenous s
pl ead. Infection of the synovium without bone or skin involvement in
the pediatric population has not been reported previously A soft tissu
e mass of the forearm in a 9-year-old boy was the initial manifestatio
n of blastomycosis. Radiographic images, ultrasound, and magnetic reso
nance imaging of the forearm could not distinguish inflammation from s
arcoma, Frozen section during open biopsy revealed a granulomatous pro
cess and several budding yeasts, There was no evidence of a malignancy
Cultures of the tissue grew Blastomyces dermatitidis. The patient was
treated successfully with surgical debridement of the mass and amphot
ericin B followed by itraconazole, for a total therapeutic course of 1
8 weeks, Although rarely diagnosed in children, blastomycosis must be
included in the differential diagnosis of any soft tissue mass.