RISK-FACTORS OF INFECTION AND DIGESTIVE-TRACT COLONIZATION BY CANDIDASPP IN A NEONATAL INTENSIVE-CARE UNIT

In this study we determined the risk factors for infection and coloniz ation by Candida spp. in our Neonatal Intensive Care Unit (NICU). We d esigned a cohort study in the NICU of the La Pat Universitary Hospital . Over a one year period, 153 neonates admitted to the NICU were studi ed. In the bivariable analysis, hospitalization period, central cathet erization, parenteral feeding, parenteral lipid feeding, respiratory s upport and premature rupture of the membranes (PRM) were statistically associated with infection and colonization; age was only associated w ith infection. Logistic regression was used to control the confusing f actors. The hospitalization period was a risk factor for infection and colonization. PRMs were also colonization risk factors. We developed a statistical equation that predicts the probability of infection or c olonization by Candida spp. that are related to a neonate's specific c haracteristics. The equation helps us to develop preventive procedures .