Anaphylactic reactions to heparin are rare. The incidence of such reac
tion has further declined after the introduction of the highly purifie
d heparin. We recently encountered a patient with unstable angina who
developed anaphylactic reaction after intravenous injection of bovine
mucous heparin sodium. The patient was successfully desensitized befor
e coronary bypass surgery, a procedure that requires the administratio
n of large doses of heparin.