Lifestyle behaviors such as cigarette smoking, weight gain during preg
nancy, and use of other drugs play an important role in determining fe
tal growth. The relationship between lifestyle risk factors and low bi
rth weight is complex and is affected by psychosocial, economic, and b
iological factors. Cigarette smoking is the largest known risk factor
for low birth weight. Approximately 20% of all low birth weight could
be avoided if women did not smoke during pregnancy. Reducing heavy use
of alcohol and other drugs during pregnancy could also reduce the rat
e of low birth weight births. Pregnancy and the prospect of pregnancy
provide an important window of opportunity to improve women's health a
nd the health of children. The adoption before or during pregnancy of
more healthful lifestyle behaviors, such as ceasing to smoke, eating a
n adequate diet and gaining enough weight during pregnancy, and ceasin
g heavy drug use, can positively affect the long-term health of women
and the health of their infants. Detrimental lifestyles can be modifie
d, but successful modification will require large-scale societal chang
es. In the United States, these societal changes should include a focu
s on preventive health, family-centered workplace policies, and change
s in social norms.