Sm. Salama et al., CHARACTERIZATION OF CHROMOSOMAL DNA PROFILES FROM HELICOBACTER-PYLORISTRAINS ISOLATED FROM SEQUENTIAL GASTRIC BIOPSY SPECIMENS, Journal of clinical microbiology, 33(9), 1995, pp. 2496-2497
The restriction endonuclease profiles of DNAs from Helicobacter pylori
strains isolated from 20 patients in two or more consecutive biopsy s
pecimens over a period of up to 2 years were analyzed by pulsed-field
gel electrophoresis with NotI and NruI. H. pylori strains possess a hi
gh degree of genomic diversity which was not observed to occur in vivo
, and attempts to observe it in vitro were not successful.