Vi. Shardakov et al., THE DEGREE OF IMMUNE DISTURBANCES AND FAC TORS INFLUENCING THEIR CORRECTION IN PATIENTS WITH CHRONIC MYELOPROLIFERATIVE DISEASES, Gematologia i transfuziologia, 40(3), 1995, pp. 6-8
Immune status in relation to tumor progression was evaluated in 175 pa
tients with chronic myeloproliferative diseases. 113 of them had chron
ic myeloid leukemia, 62 chronic subleukemic myelosis. It was establish
ed that immunologic reactivity decline correlated with the rate of tum
or progression. The degree of immune deficiency should be taken into c
onsideration in selection of patients for immunotherapy.