Cc. Murphy et al., PREVALENCE OF EPILEPSY AND EPILEPTIC SEIZURES IN 10-YEAR-OLD CHILDREN- RESULTS FROM THE METROPOLITAN ATLANTA DEVELOPMENTAL-DISABILITIES STUDY, Epilepsia, 36(9), 1995, pp. 866-872
With reported prevalence rates of 4-9 cases per 1,000 children, childh
ood epilepsy is a major public health concern. Reported prevalence rat
es vary, mainly because researchers often use different epilepsy defin
itions, In addition, total prevalence may be underestimated if incompl
ete case-ascertainment methods are used. We used a multiple-source cas
e-ascertainment method that included obtaining information from electr
oencephalogram laboratories to estimate the prevalence of epilepsy and
to classify seizure types among 10-year-old children. In the metropol
itan Atlanta (GA, U.S.A.) area, we found a lifetime prevalence of chil
dhood epilepsy of 6 per 1,000 (95% confidence interval, 5.5-6.5) 10-ye
ar-old children. However, using capture-recapture analysis, this preva
lence may be as high as 7.7 per 1,000. Proportionately more boys than
girls had epilepsy, The prevalence did not vary appreciably by race. P
artial seizures, including secondarily generalized seizures, were the
most common seizure type (58%). Of children with epilepsy, 35% had ano
ther developmental disability (mental retardation, cerebral palsy, vis
ual impairment, or hearing impairment). An accurate estimate of the pu
blic health burden of childhood epilepsy and determination of possible
risk factors for idiopathic epilepsy both depend on conducting comple
te community-based case ascertainment and obtaining detailed clinical
data.