The widely used polar plasticizer 2-nitrophenyl octyl ether (NPOE) is
found to act as a dynamic quencher of the luminescence of certain indi
cators; quenching studies have been performed both in solution and sen
sor membranes plasticized with NPOE. A series of 2-cyanophenyl alkyl e
thers (with C-8, C-10 and C-12 alkyl chains) has been prepared and is
found not to act as quenchers and hence, represent an improved crass o
f plasticizers for use in luminescence-based sensors.