THE INFLUENCE OF DIFFERENT FLUORIDE SALTS ON FLUORIDE-MEDIATED INHIBITION OF PEROXIDASE-ACTIVITY IN HUMAN SALIVA

Fluoride-mediated inhibition of peroxidase potential activity in human saliva was investigated using NaF, NH4F, CaF2, Na2PO3F (MFP), SnF2 an d TiF4. At pH 5.5 and for a 20 mM F concentration, the inhibition perc entages increased from 2% for MFP and 5% for CaF2 to 61% for NaF and 6 5% for NH4F, while a 100% inhibition was observed at 10 mM for TiF4 an d at 5 mM for SnF2. The inhibition was enhanced at acid pH and removed at pH 7. The inhibition could be attributed to ionized F-, except for SnF2 and TiF4, in which part of the inhibition could be imputed to th e cations.