Je. Muscat et El. Wynder, EXPOSURE TO ENVIRONMENTAL TOBACCO-SMOKE AND THE RISK OF HEART-ATTACK, International journal of epidemiology, 24(4), 1995, pp. 715-719
Background. Environmental tobacco smoke (ETS) increases the risk of he
art disease in several epidemiological studies although the methods of
assessing exposure have been incomplete. We determined the prevalence
of ETS from various sources, and examined the association between ETS
and the risk of myocardial infarction. Methods. A hospital-based case
-control study of myocardial infarction was conducted from 1980 to 199
0 by interviewing 114 case patients and 158 control subjects. Results.
Among controls, the sources of ETS were the workplace (56%), childhoo
d exposure (66%), home adult exposure (48%), car exposure (20%) and fr
om trains or other surface transportation (4%). Compared to never smok
ers, the odds ratio (OR) for exposure to ETS during childhood was 0.97
(95% confidence intervals [CI] :0.53-1.46) for men and 0.92 (95% CI :
0.5-1.86) for women. The adjusted OR associated with adult exposure wa
s 1.5 (95% CI : 0.9-2.6), although no trend was observed with the numb
er of years of exposure. Women who were exposed to ETS in automobiles
had an increased but non-significant risk (OR = 2.8, 95% CI :0.9-8.0).
Conclusion. Exposure to ETS comes from a variety of sources besides t
he spouse including parents, workplace employees and motorists. Exposu
re to ETS during childhood is not associated with an increased risk of
heart disease. However, ETS exposure during adulthood increased the r
isk of myocardial infarction approximately 50% in this data although t
he findings were not statistically significant.