Background. The mortality level from all causes is different between p
opulations and it has decreased for both men and women in most countri
es in the last decades. However, there is a difference in the male/fem
ale sex ratio of mortality between populations and its time trends and
the reasons for these differences remain unclear. Methods. The sex ra
tio of all-cause mortality and the main causes of death, i.e. total ca
rdiovascular disease and cancer, for 30 populations in 1988 (mean of 1
987-1989), and the time trends of the sex ratio for 27 populations are
analysed. Results. Large differences in the sex ratio of mortality ex
ist among the studied populations, The sex ratio of all-cause, total c
ardiovascular and cancer mortality markedly increased in most countrie
s during recent decades. Conclusions. The sex ratio of all-cause morta
lity and its time trends correlated significantly and positively with
the sex ratio of mortality and its time trends from total cardiovascul
ar disease and cancer. The differences of the sex ratio of mortality a
nd their time trends between populations cannot be explained by geneti
c factors. They could be attributed to differences in life style. A di
fferent exposure and different reaction to the risk factors of cardiov
ascular diseases and cancer, e.g. saturated fat intake, alcohol intake
and smoking habits, between men and women are considered to be the ma
in causes for these differences in the sex ratio of mortality.