USE OF AIDS SURVEILLANCE DATA TO DESCRIBE SUBEPIDEMIC DYNAMICS

Background. Official reports on AIDS surveillance mainly consist of ab solute numbers of AIDS cases or cumulative incidence rates. More detai led analyses focusing on the clusters of subepidemics within Italy see med necessary for a better understanding and more accurate description of the epidemic. Methods. Age-specific AIDS incidence rates were calc ulated with reference to resident population by sex, calendar time and geographical area. Age-standardized incidence rates, with the Italian resident population in 1990 as standard, were used to present time tr ends and geographical distributions. All analyses were repeated for in jecting drug users, homosexual/bisexual men, heterosexual contacts and individuals with other or undetermined risk factors. Results. Annual incidence rates for AIDS in Italy increased over the study period. The highest rates were observed in the North and in Sardinia, while South ern regions showed generally lower rates. This heterogeneity was more evident when examining small geographical areas (i.e. provinces). Epid emics in some of the smaller provinces, such as Imperia and Livomo (No rthwestern port towns), were shown to be important in that they greatl y affect AIDS incidence rates in the regions in which they are located . Conclusions. According to our analysis, the crude presentation of da ta from the Italian AIDS Registry is not adequate for understanding th e national spread of the AIDS epidemic in terms of several local subep idemics, which may differ by size, temporal trend, and risk group comp osition. Classifying cases according to their place of residence, whic h we considered as a good proxy of the place of life, was fundamental for correctly locating these subepidemics. Furthermore, the use of age -standardized rates allowed for unbiased comparisons between regions w hose population may have a different age structure and dynamics.