The nucleotide sequence of the structural gene for isocitrate lyase (a
cu-7) is presented and features of its coding sequence and predicted p
rotein are described. Several motifs were identified within the promot
er region which are potentially involved in transcriptional regulation
. Surprisingly, some of these occur within the coding sequence of an a
djacent gene of unrelated function that terminates within 371 bp upstr
eam from acu-7. The sequence of this second gene identified an N-acety
lglucosamine-1-phosphate transferase.