Dj. Evans et al., SYMPTOMATIC VITAMIN-E-DEFICIENCY DIAGNOSED AFTER HISTOLOGICAL RECOGNITION OF MYOMETRIAL LIPOFUSCINOSIS, Lancet, 346(8974), 1995, pp. 545-546
We report a 44-year-old woman in whom intestinal bypass for obesity at
age 23 resulted in chronic malabsorption. After hysterectomy for meno
rrhagia due to atypical endometrial hyperplasia, the finding of myomet
rial lipofuscinosis led to a demonstration of vitamin E deficiency. Vi
tamin E supplementation led to an unexpected improvement in the unstea
diness of gait and slurring of speech of which she had also complained
. We suggest that supplementation with vitamin E should be routine in
all patients with persistent severe steatorrhoea.