OBJECTIVE. The role of stereotaxic core biopsy in evaluating mammograp
hically detected lesions that have a high probability of being maligna
nt is still debated, This study was undertaken to assess the use of st
ereotaxic core biopsy in evaluating spiculated masses, by determining
the frequency with which core biopsy reduced the number of surgical pr
ocedures performed in the management of these highly suspicious lesion
s. MATERIALS AND METHODS. Forty-three impalpable spiculated breast mas
ses in 43 patients were sampled with stereotaxic core biopsy, All pati
ents underwent surgery. Patient charts were reviewed to determine the
histopathologic findings at stereotaxic core biopsy and at surgery, an
d the number and type of surgeries performed. RESULTS. Invasive carcin
oma was identified at stereotaxic core biopsy in 40 (93%) of 43 patien
ts. Therapeutic surgical procedures were lumpectomy in 28 patients (22
with axillary dissection) and mastectomy in 12. The presence of tumor
at the lumpectomy margins led to subsequent mastectomy in one case. O
ne lesion yielded atypical ductal hyperplasia at core biopsy; surgical
biopsy revealed ductal carcinoma in situ. Surgical biopsy was recomme
nded in two lesions yielding benign histologies at core biopsy and rev
ealed invasive ductal carcinoma in one. Thirty-three (77%) of 43 patie
nts had the number of surgical procedures reduced by stereotaxic core
biopsy; these were patients with carcinoma diagnosed at core biopsy wh
o underwent one-stage lumpectomy with axillary lymph node dissection o
r mastectomy. CONCLUSION. Stereotaxic core biopsy reduced the number o
f surgical procedures in most women with impalpable spiculated breast
masses. These data suggest that stereotaxic core biopsy is a valuable
diagnostic technique for assessing these lesions, which are likely to
represent carcinoma.