KINETIC-BEHAVIOR OF PENICILLIN ACYLASE SABILIZED BY POLY(ETHYLENEIMINE)

The paper presents the kinetic evaluations of poly(ethyleneimine)-peni cillin acylase preparations. The comparative studies show that the inv estigated system is much better than the native enzyme, and slightly w orse than commercially available Boenringer preparation. Additionally, the high stability of PEI-enzyme system, very easy way of its prepara tion, high flexibility, and possibility to set the needed enzyme conce ntration are particularly favourable for use of the membrane bioreacto r with PEI-enzyme system immobilized in its volume. Some advantages of the use of such bioreactor are also discussed.