SUCCESSFUL TREATMENT OF AN ADVANCED INTERSTITIAL PREGNANCY BY SEQUENTIAL SYSTEMIC AND LOCAL-ADMINISTRATION OF METHOTREXATE

Authors
HOEK A BROEKMANS FJ VERHEIJEN RHM SCHATS R
Citation
A. Hoek et al., SUCCESSFUL TREATMENT OF AN ADVANCED INTERSTITIAL PREGNANCY BY SEQUENTIAL SYSTEMIC AND LOCAL-ADMINISTRATION OF METHOTREXATE, Human reproduction, 10(7), 1995, pp. 1864-1865
Citations number
13
Categorie Soggetti
Reproductive Biology
Journal title
Human reproduction → ACNP
ISSN journal
02681161
Volume
10
Issue
7
Year of publication
1995
Pages
1864 - 1865
Database
ISI
SICI code
0268-1161(1995)10:7<1864:STOAAI>2.0.ZU;2-N
Abstract
A patient is presented with an advanced interstitial pregnancy, diagno sed by transvaginal ultrasound and confirmed by laparoscopy, Amenorrho ea at the time of diagnosis was 57 days, Methotrexate was given system ically (4x50 mg i.m.), Because of persisting viability of the fetus, s ystemic methotrexate treatment was followed by local instillation of m ethotrexate into the gestational sac (50 nag), FoIlow-up revealed rapi d human chorionic gonadotrophin regression but slow regression of feta l remnants.