This article gives an overview of the final report of the National Ins
titutes of Health (NIH) Embryo Research Panel, which was issued on Sep
tember 27, 1994 (NIH, 1994), The report was endorsed unanimously by th
e Advisory Committee to the Director of the NIH, Harold Varmus, on Dec
ember 2, 1994, A few hours later, President Clinton (Marshall, 1994) i
ssued a statement announcing that he did 'not believe that federal fun
ds should be used to support the creation of human embryos for researc
h purposes', and that he had directed the NIH not to support such rese
arch, which was one of the areas of research recommended for Federal f
unding by the Panel. At present, Dr Varmus is in the process of consid
ering the Panel's report and shaping guidelines to govern the review a
nd conduct of human embryo research, Any guidelines will be published
in the Federal Register for comment at a later date, As a result of ch
anges brought about by Congress in 1993, Federal support for research
focused on in-vitro fertilization (IVF) could go forward, This represe
nted the first advance in research freedom in the Federal sector to st
udy approaches to IVF. It will involve the NIH in peer review and scie
ntific activities regarding IVF. Assuming that Dr Varmus develops guid
elines to support human embryo research limited to use of 'spare' embr
yos only and perhaps parthenogenotes, a second step will have been tak
en, My view about the context and meaning of the President's decision,
which is nonetheless a decided step to the rear, appears in the final
part.