HDL-CHOLESTEROL INCREASE ASSOCIATED TO TRIGLYCERIDES DEGRADATION IN-VITRO

The effect of muscle tissue from rats trained by swimming on the extra cellular degradation of triglyceride (TG) rich particles has been stud ied in vitro. During incubation, there is a progressive decline of the TG concentration in the incubation medium. At the end of the incubati on period (90 min), a significantly reduction in the TG levels (p < 0. 05) is associated with a significant increase in the high-density lipo protein (HDL) cholesterol level (p < 0.005). There are no significant changes in total cholesterol levels. The correlation of the TG decline with the HDL-cholesterol increase is significant (r = 0.695, p < 0.05 , n = 25). The experimental model used here could be of great interest for the in vitro study of factors affecting lipid levels in plasma.