K. Mohammadali et al., GORILLA AND ORANGUTAN C-MYC NUCLEOTIDE-SEQUENCES - INFERENCE ON HOMINOID PHYLOGENY, Journal of molecular evolution, 41(3), 1995, pp. 262-276
The nucleotide sequences of the gorilla and orangutan myc loci have be
en determined by the dideoxy nucleotide method. As previously observed
in the human and chimpanzee sequences, an open reading frame (ORF) of
188 codons overlapping exon 1 could be deduced from the gorilla seque
nce. However, no such ORF appeared in the orangutan sequence. The two
sequences were aligned with those of human and chimpanzee as hominoids
and of gibbon and marmoset as outgroups of hominoids. The branching o
rder in the evolution of primates was inferred from these data by diff
erent methods: maximum parsimony and neighbor-joining. Our results sup
port the view that the gorilla lineage branched off before the human a
nd chimpanzee diverged and strengthen the hypothesis that chimpanzee a
nd gorilla are more related to human than is orangutan.