PURPOSE: To analyze the structural changes seen at computed tomography
(CT), particularly the findings that precede insufficiency (fatigue)
fractures in massive osteoarticular knee allografts. MATERIALS AND MET
HODS: The subchondral and cancellous bone of 12 allografts were retros
pectively evaluated with repeat transaxial CT (mean follow-up, 53 mont
hs). RESULTS: Early cortical graft resorption was followed by slow thi
ckening after 6 months. Formation of resorptive cysts increased the co
rtical irregularity, which leveled off after 2 years. Late remodeling
was evident as a subcortical sclerotic rim,''neocortex.'' Initially, t
he cancellous graft bone showed higher attenuation than the host bone;
this difference subsided gradually during the first 3 years. Four ins
ufficiency fractures were detected after the Ist postoperative year. P
oor remodeling preceded these fractures. CONCLUSION: CT effectively de
picted the structural changes during allograft incorporation and was s
uperior to plain radiography for the detection of insufficiency fractu
res. The use of CT for follow-up of massive osteoarticular knee allogr
afts provides additional information concerning the readiness of the g
raft for weight bearing.