DIROFILARIA REPENS INFECTION IN NORTHERN ISRAEL

The fourth case of zoonotic Dirofilaria repens infection in Israel is reported, and the diagnostic morphologic characteristics of this filar iid are reviewed. The importance of the exact anatomic diagnosis of th is filaria is stressed in view of the fact that Israel has pockets of settlers from East Africa, a region endemic for lymphatic filariasis ( Wuchereria bancrofti). Since the possibility of introduction of such a n infection into the country exists, differentiating this zoonotic Dir ofilaria from other filarial worms is essential. The clinicopathologic al features of a Dirofilaria repens infection are distinct. The patien t initially has a painful subcutaneous or conjunctival swelling; the e xcisional biopsy shows the presence of a dead or alive, usually female worm that measures 220-660 mu m across; the central intestine and the genital organs (two uteri) are located in the pseudocoelom; the thick , multilayered cuticle is provided with 95-105 sharp, longitudinal rid ges, the latter being separated from each other by a distance of 12 mu m; the circumferential muscle cell layer, covering the inner side of the cuticle, is bilaterally interrupted by the large chord cells, two to five nuclei of which are discernible in each cross section.