NEEDLE-TYPE GLUCOSE BIOSENSOR WITH AN ELECTROCHEMICALLY CODEPOSITED ENZYME IN A PLATINUM BLACK MATRIX

In this study we report the development of a needle-type glucose biose nsor for the management of hemorrhagic shock. The immobilization techn ique depends on the electrophoretic deposition of the glucose oxidase enzyme in an electrochemically grown platinum black matrix. The sensor was coated with Nafion to decrease the effect of interferents. Prelim inary tests were carried out to evaluate the sensor performance in vit ro. These tests included the measurement of glucose levels in buffer s olutions containing various potential physiological interferents, as w ell as in bovine serum. The preliminary results show the sensor to hav e linearity up to 33 mM and a diminished response to interferents. The advantages of this technique are its simplicity and high controllabil ity.