With increased signal-to-noise, spatial, temporal, and spectral resolu
tion, blood oxygenation level contrast, and other benefits of high fie
ld NMR, 4T NMR systems enhance the potential for using multinuclear im
aging and spectroscopy for medical science and clinical diagnostics. A
new NMR spectrometer is needed however. The magnet aside, the key dif
ference between present clinical or animal systems, and 4T+ clinical s
ystems is the RF front end. Including the power amplifier, transmit/re
ceive (T/R) switch, preamplifier, and RF coils, the front end is requi
red to operate at power levels, bandwidths, and circuit lengths unique
in the NMR field. New technology has been developed for these compone
nts to optimize the performance of the spectrometer. To cover broader
spectral bandwidths, and to compensate for chemical shift dispersion e
rror, two 15kW solid stare amplifiers have been developed for implemen
tation on a ''home-built'' 4.1T clinical system. A stripline transform
ed, nonmagnetic, tuned GaAsFET preamp has been built for achieving hig
h gain and low noise at the RF coil. A nonmagnetic dual quadrature hyb
rid-PIN diode T/R switch was developed to isolate the RF power amplifi
er from the receiver. New high frequency coils have made use of tuned
cavities and transmission lines.