Purpose: To determine whether the use of Gluma as a desensitizing agen
t on tooth preparations has any effect upon the bond strength of a res
in composite restoration cemented to dentin. Materials and Methods: Fo
rty extracted human molars which were caries and restoration-free were
occlusally reduced to remove enamel. Twenty of the teeth received a G
luma desensitization treatment and 20 were untreated (controls). Follo
wing a 7-day storage period, simulated resin composite inlays were bon
ded to all of the dentin specimens, using either All-Bond 2 with All-B
ond Crown and Bridge Cement or OptiBond with Porcelite Dual Cure. Twen
ty-four hours later, the shear bond strength of the specimens was dete
rmined. Results: Statistical analysis (paired t-tests) indicated no si
gnificant difference in bond strength for Gluma-treated specimens when
compared to controls, for either bonding material.