Purpose: To evaluate the anticalculus effect of three commercial denti
frices. Materials and Methods: A 12-week independent and double-blind
clinical study was conducted on a population of calculus-forming adult
male and female subjects in Budapest, Hungary to directly compare the
anticalculus efficacy of three commercially-available dentifrices, as
compared to a placebo dentifrice. The three commercially-available an
ticalculus dentifrices compared in this clinical study to a 0.243% sod
ium fluoride/silica placebo dentifrice were as follows: (1) A dentifri
ce containing 1.3% soluble pyrophosphate and 1.5% of a PVM/MA copolyme
r in a 0.243% sodium fluoride/silica base. (2) A dentifrice containing
0.3% triclosan and 2% of a PVM/MA copolymer in a 0.243% sodium fluori
de/silica base. (3) A dentifrice containing 0.3% triclosan and 0.75% z
inc citrate in a 1.14% sodium monofluoro-phosphate/silica base. Result
s: All three anticalculus dentifrices provided statistically significa
nt reductions in supragingival calculus formation, as compared to a pl
acebo dentifrice, after 12 weeks of use. The reductions in supragingiv
al calculus formation ranged from 39% to 55%, as compared to a placebo
dentifrice, for the three commercially-available anticalculus dentifr
ices. There was no statistically significant difference among the thre
e commercially-available dentifrices with regard to anticalculus effic
acy.