SYNTHETIC, STRUCTURAL AND ANTIMICROBIAL STUDIES OF SOME MACROCYCLIC LIGANDS AND THEIR COPPER(II) COMPLEXES

Four new macrocyclic complexes, Cu(DPIH)(BF4)(2), Cu(DPDH)(BF4)(2), Cu (DCIH)(BF4)(2) and Cu(DCPDH)(BF4)(2), where DPIH = 2,6-diacetylpyridin e-N-iminodiacetoylhydrazone, DPDH = tylpyridine-N-pyridine-2,6-dicarbo xyloylhydrazone, DCM = idinedicarbonyldichloride-N-iminodiacetoylhdraz one and DCPDH = ldichloride-N-pyridine-2,6-dicarboxyloylhydrazone, hav e been synthesised. The in vitro antimicrobial studies revealed that t he macrocyclic complexes are potentially active against a few bacteria and fungi and exhibit greater biocidal effect as compared to the liga nd fragments.