SYNTHESIS OF N-GLYCOSYLATED PYRIDINES AS NEW ANTIVIRAL AGENTS

Authors
IBRAHIM ES ELGEMEIE GEH ABBASI MM ABBAS YA ELBADAWI MA ATTIA AME
Citation
Es. Ibrahim et al., SYNTHESIS OF N-GLYCOSYLATED PYRIDINES AS NEW ANTIVIRAL AGENTS, Nucleosides & nucleotides, 14(6), 1995, pp. 1415-1423
Citations number
12
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
14
Issue
6
Year of publication
1995
Pages
1415 - 1423
Database
ISI
SICI code
0732-8311(1995)14:6<1415:SONPAN>2.0.ZU;2-R
Abstract
A series of 3-cyanopyridine glycosides have been synthesized and evalu ated for their inhibitory activity against human immunodeficiency viru s (HIV) replication in MT-4 cells. Among the 3-cyanopyridine glycoside s 6-(p-methylphenyl) and 6-(p-aminophenyl) were the most selective inh ibitors of HIV replication.