SYNTHESIS AND ANTIVIRAL ACTIVITY OF SOME N-PENTOPYRANOSYL-2-PYRIDINETHIONES

Citation
Ame. Attia et al., SYNTHESIS AND ANTIVIRAL ACTIVITY OF SOME N-PENTOPYRANOSYL-2-PYRIDINETHIONES, Nucleosides & nucleotides, 14(7), 1995, pp. 1581-1590
Citations number
12
Categorie Soggetti
Biology
Journal title
ISSN journal
07328311
Volume
14
Issue
7
Year of publication
1995
Pages
1581 - 1590
Database
ISI
SICI code
0732-8311(1995)14:7<1581:SAAAOS>2.0.ZU;2-3
Abstract
A novel synthesis of 1-(beta-D-pentopyranosyl)pyridinethione nucleosid es utilizing pyridine-2(1H)-thiones and alpha-bromoxylose or beta-brom oarabinose triacetate as starting components is described. The free nu cleosides were tested for their potential activity against HIV and dif ferent types of tumor virus.