CONFORMATIONAL-ANALYSIS OF THE ERYTHROMYCIN ANALOGS AZITHROMYCIN AND CLARITHROMYCIN IN AQUEOUS-SOLUTION AND BOUND TO BACTERIAL-RIBOSOMES

Authors
AWAN A BRENNAN RJ REGAN AC BARBER J
Citation
A. Awan et al., CONFORMATIONAL-ANALYSIS OF THE ERYTHROMYCIN ANALOGS AZITHROMYCIN AND CLARITHROMYCIN IN AQUEOUS-SOLUTION AND BOUND TO BACTERIAL-RIBOSOMES, Journal of the Chemical Society, Chemical Communications, (16), 1995, pp. 1653-1654
Citations number
21
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
16
Year of publication
1995
Pages
1653 - 1654
Database
ISI
SICI code
0022-4936(1995):16<1653:COTEAA>2.0.ZU;2-M
Abstract
The conformations of erythromycin A 9-ketone, azithromycin and clarith romycin free in aqueous solution and weakly bound to bacterial ribosom es are determined using ROESY and transferred NOESY H-1 NMR experiment s.