Y. Ding et Xr. Jiang, A NOVEL HIGHLY STEREOSELECTIVE SYNTHESIS OF THE A-RING OF TAXOL VIA 2ALDOL REACTIONS, Journal of the Chemical Society, Chemical Communications, (16), 1995, pp. 1693-1694
An efficient, scalable route to the Taxol A-ring synthon is described;
high stereoselectivity and regioselectivity are achieved by means of
an intermolecular Aldol addition and an intramolecular Aldol condensat
ion.