A. Leelaporn et al., MULTIDRUG-RESISTANCE PLASMID PSK108 FROM COAGULASE-NEGATIVE STAPHYLOCOCCI - RELATIONSHIPS TO STAPHYLOCOCCUS-AUREUS QACC PLASMIDS, Plasmid, 34(1), 1995, pp. 62-67
The 2.4-kb Staphylococcus epidermidis plasmid, pSK108, encodes a qacC
multidrug resistance determinant. Sequence analysis has revealed that
pSK108 is a member of the pC194 family of rolling circle replicating p
lasmids and suggests that the DNA segment containing qacC, which is bo
unded by the replication nick site and the minus origin palA represent
s a resistance gene cassette that has undergone horizontal genetic exc
hange. (C) 1995 Academic Press, Inc.