F. Gregori et al., COX MAZE OPERATION WITHOUT CRYOABLATION FOR THE TREATMENT OF CHRONIC ATRIAL-FIBRILLATION, The Annals of thoracic surgery, 60(2), 1995, pp. 361-363
Background. From August 1993 to May 1994, 20 patients (mean age, 43 ye
ars) with atrial fibrillation underwent the maze operation without cry
oablation. Ten patients had mitral stenosis, 5 had mitral insufficienc
y, and 5 had a mixed mitral lesion. The mean left atrial diameter as m
easured on echocardiograms was 6.1 cm. The cause was rheumatic in 17 p
atients (85%) and degenerative in 3 (15%). Seven patients had had prev
ious episodes of thromboembolism. Methods. Mitral valvuloplasty was pe
rformed on 7 patients, mitral commissurotomy on 4, and mitral valve re
placement on 9. Thrombi were found in the left atrium of 7 patients an
d also in the right atrium in 2. The mean cross-clamp time was 73 minu
tes (range, 52 to 108 minutes). Results. Patients were discharged from
the hospital in good condition. Hemodynamic studies and Doppler echoc
ardiograms showed significant reduction in the left atrial diameter (m
ean diameter, 4.9 cm; p < 0.01) in 18 patients. The two-channel Holter
monitor showed sinus rhythm in 15 patients, atrial ectopic rhythm in
4, and atrial fibrillation in 1. Eleven patients (55%) experienced atr
ial fibrillation (9 in the first 3 months postoperatively), which was
reversed with quinidine. Ninety percent of patients had development of
an effective, synchronous, atrial systole. Six to 15 months postopera
tively (average follow-up, 10 months), all patients were in functional
class I, and 18 were not on a regimen of antiarrhythmic medication. C
onclusions. This simplification of the maze operation has been demonst
rated to be an effective alternative for the treatment of chronic atri
al fibrillation.