Objective: To survey the nonsurgical diagnostic techniques for disting
uishing adenomyosis, and to determine whether one technique offers dia
gnostic advantages. Data Sources: We conducted a thorough search of th
e MEDLINE data base and identified English-language papers on adenomyo
sis published during the last 28 years. Reference lists of retrieved a
rticles were also examined for additional source documents. Methods of
Study Selection: We reviewed 238 articles. Papers on nonsurgical diag
nostic techniques published in peer-reviewed journals were selected fo
r inclusion. Data Extraction and Synthesis: We determined nonsurgical
diagnostic techniques for distinguishing adenomyosis to be hysterosalp
ingography, abdominal ultrasound, transvaginal sonography, and magneti
c resonance imaging (MRI). Studies were divided into these four catego
ries, reviewed, and summarized accordingly. Recent reports suggest tha
t noninvasive modalities, eg, transvaginal sonography and MRI, have ma
de possible the nonsurgical diagnosis of adenomyosis. Conclusion: Beca
use of its widespread availability and patient tolerance, transvaginal
sonography remains the primary screening modality for imaging the fem
ale pelvis. However, for cases in which sonography cannot detect adeno
myosis, MRI provides a viable alternative and should be the definitive
diagnostic modality of choice.