Aim: To know the prevalence of anti-VHC in the Valencia Male Penitenti
ary Centre. Design: A prospective study in which a representative samp
le of the inmates is included. In each case the anti-VHC and the ALT a
re studied. Serological results were correlated with history of intrav
enous drug addiction, alcohol abuse and duration and number of internm
ents. inmates: 750 inmates are included; they represent 41% of the peo
ple interned in this Centre during 1991. Results: A high prevalence (4
5%) of the serological marker for VHC infection was observed. The prev
alence of anti-VHC+ among the drug addict inmates is around 90% and th
is situation was already found during the first year of drug addiction
. Among non-drug addict inmates the prevalence is 14%. Hepatitis C vir
us infection has a correlation with the duration and number of interme
nts; 75% of the inmates with high ALT values have anti-VHC+. Conclusio
ns: Nearly half of the inmates are infected with hepatitis C virus. Th
e drug addict inmates are infected during the first year of their habi
t. The majority of the inmates with elevated ALT has antiVHC +.