AN EFFICIENT SYNTHESIS OF THE METHYL-ESTER OF BENZOLEUKOTRIENE B-3, ALEUKOTRIENE B-4 ANALOG

Authors
BABUDRI F FIANDANESE V MARCHESE G PUNZI A
Citation
F. Babudri et al., AN EFFICIENT SYNTHESIS OF THE METHYL-ESTER OF BENZOLEUKOTRIENE B-3, ALEUKOTRIENE B-4 ANALOG, Synlett, (8), 1995, pp. 817-818
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
8
Year of publication
1995
Pages
817 - 818
Database
ISI
SICI code
0936-5214(1995):8<817:AESOTM>2.0.ZU;2-1
Abstract
The synthesis of benzoleukotriene B-3 methyl ester has been easily ach ieved by a palladium-catalyzed dienylstannane/aryl halide coupling rea ction. A selective and sequential electrophilic substitution with acyl chlorides, followed by a reduction reaction, leads to the title compo und.