THE PALLADIUM-CATALYZED CARBONYLATIVE COUPLING OF 5-(TRIMETHYLSILYLETHYNYL)-3',5'-DI-O-ACETYL-2' DEOXYURIDINE AND 1-ALKYNES WITH ARYL IODIDES

Authors
ARCADI A CACCHI S MARINELLI F PACE P SANZI G
Citation
A. Arcadi et al., THE PALLADIUM-CATALYZED CARBONYLATIVE COUPLING OF 5-(TRIMETHYLSILYLETHYNYL)-3',5'-DI-O-ACETYL-2' DEOXYURIDINE AND 1-ALKYNES WITH ARYL IODIDES, Synlett, (8), 1995, pp. 823-824
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
8
Year of publication
1995
Pages
823 - 824
Database
ISI
SICI code
0936-5214(1995):8<823:TPCCO5>2.0.ZU;2-L
Abstract
The palladium-catalysed reaction of hylsilylethynyl)-3',5'-di-O-acetyl -2'-deoxyuridine with aryl iodides in the presence of n-Bu(4)NF and tr iethylamine under a balloon of carbon monoxide produces (2-acylethynyl )-3',5'-di-O-acetyl-2'-deoxyuridines in good yields at room temperatur e. The methodology has been extended to the preparation of alpha,beta- ynones from 1-alkynes and aryl iodides.