J. Ezquerra et al., NEW ENANTIOSELECTIVE APPROACH TO ALPHA-ALLOKAINOIDS BY MICHAEL ADDITION TO CHIRAL 4-SUBSTITUTED 2,3-DIDEHYDROPROLINATE, Tetrahedron letters, 36(34), 1995, pp. 6149-6152
(-) and (+) alpha-Allokainoids hydrochlorides 3 and 4 were obtained by
hydrolysis of the corresponding Michael adducts resulting from the ad
dition of diethyl malonate to chiral N-urethane protected ethyl 4-benz
yl-2,3-didehydroprolinates 9 and 13 respectively.