IN-VITRO DEVELOPMENT OF RESISTANCE TO BETA-LACTAM ANTIBIOTICS IN STREPTOCOCCUS-PNEUMONIAE

Authors
CARSENTIETESSE H DURANT J SALVADOR F BENSOUSSAN M BENSOUSSAN F PRADIER C THABAUT A DELLAMONICA P
Citation
H. Carsentietesse et al., IN-VITRO DEVELOPMENT OF RESISTANCE TO BETA-LACTAM ANTIBIOTICS IN STREPTOCOCCUS-PNEUMONIAE, Journal of antimicrobial chemotherapy, 36(2), 1995, pp. 417-423
Citations number
12
Categorie Soggetti
Microbiology,"Pharmacology & Pharmacy
Journal title
Journal of antimicrobial chemotherapy → ACNP
ISSN journal
03057453
Volume
36
Issue
2
Year of publication
1995
Pages
417 - 423
Database
ISI
SICI code
0305-7453(1995)36:2<417:IDORTB>2.0.ZU;2-O
Abstract
Selection of resistant mutants was induced in broth by exposing pneumo cocci to serial sub-inhibitory concentrations of various beta-lactam a ntibiotics. Aminopenicillins selected for resistance to themselves and to cephalosporins although cephalosporins tended to select for resist ance to their own class, with the exception of cefixime which seems to select cross-resistant organisms.